In 2022, the world's first nebulized inhalation new crown vaccine was launched, breaking the traditional route of vaccine administration. Not only has it shown good safety and immunogenicity in clinical data, but it can also induce mucosal immunity, which has brought a breakthrough in the development of respiratory vaccines.
Meanwhile, the first nebulized inhalation antibiotic tobramycin inhalation solution for the treatment of bronchiectasis was listed on the market, which changed the status quo that no drug was available in China in the field of nebulized inhalation treatment for bronchiectasis patients, providing more support for bronchiectasis patients and improving their quality of life.
Nebulized Inhalation Therapy: An Innovative Way to Expand the Field of Treatment
Nebulized inhalation therapy (NIT) is a method of drug delivery in which drugs are atomized by a special drug delivery device and inhaled into the lungs by the patient in the form of an aerosol to exert a local or systemic effect for preventive, therapeutic or diagnostic purposes. It is the preferred method of drug delivery for the treatment of asthma and chronic obstructive pulmonary disease (COPD), and can also be used for the treatment of pulmonary fibrosis, lung cancer and other respiratory diseases.
With the continuous development of nebulized medicine, nebulized therapy is no longer limited to the classic nebulized drugs such as budesonide and salbutamol, but scientists are now doing more research in new areas, and nebulized inhalation therapy has been shown to be an alternative to injectable routes of administration of peptides and proteins in situations such as systemic administration of medications, gene therapy, or vaccine administration. The above mentioned drugs that have been on the market for a short period of time are good examples of this.
Nebulizer Science: A Comparative Analysis of Compression Nebulizers and Mesh Nebulizers
There are two types of nebulizers currently used to deliver medications, namely compression nebulizers and mesh nebulizers. Compression nebulizer, also known as jet nebulizer, is powered by compressed air or oxygen, through the high-speed airflow generated for inhalation of aerosol atomization device, mainly by the air source, nebulizer cups and masks or suction nozzle composition. Its atomization efficiency is relatively low, the atomization time is long, and generally causes a relatively large residue.
The other is a mesh nebulizer also called vibrating screen nebulizer, through the vibration of the screen, the liquid produces periodic pressure, so that the liquid is squeezed and sprayed through the mesh. The nebulization method is softer, which will reduce the destruction of biologically active drugs. Vibrating screen nebulizer has the advantages of shorter nebulization time, high drug utilization, high output water mist FPF, no requirement for patient's respiratory ability and hand-mouth coordination, and makes it easy to carry and use, and so on.
AiMesh® Polymer Membrane Technology: A Safety Tool to Enhance the Performance of Mesh Atomizers
The core of a mesh nebulizer is the 'mesh', i.e. the membrane. feellife®'s patented AiMesh® polymer membrane technology can further enhance the performance of mesh nebulizers, thus obtaining a better liquid throughput rate, reducing the blockage of the holes, and greatly reducing the risk of rust or breakage of the holes, thus improving safety. This polymer diaphragm technology is not only a symbol of technological innovation, but also the key to improving safety and efficiency.
The further development of nebulized inhalation therapy not only improves the treatment experience for patients, but also brings great opportunities for innovation in the medical research and pharmaceutical fields. Advances in technology have opened up a broader perspective for nebulized medicine, demonstrating the potential of this treatment modality in the future of medical therapy. As technology continues to advance, our expectations for nebulized medicine will become even broader, and we believe that this field will bring more surprises to the future of medical treatment.