Nebulizing inhalation combined with non-invasive ventilation therapy in COPD patients with respiratory failure and nursing． XU Xiao-ya，JIANG Mei-fang，WANG Yong-sheng，et al． China Aviation Industry 363 Hospital，Chengdu，Sichuan 610041，China

【Abstract】 Objective To explore the application and nursing of oxygen-driven inhalation joint with non-invasive ventilation therapy in COPD patients with respiratory failure． 

Methods 39 cases diagnosed COPD with respiratory failure during January 2011 to December 2012 in our department were randomly divided into two groups: the experimental group( 21 cases) and control group( 18cases) ． The eperimental group useing non-invasive ventilation combined oxygen-driven inhalation otherwise the control group using conventional inhalation therapy ( off-hook inhalation) ． Compare the improving of hypoxia，carbon dioxide retention, dyspnea，difficulty in expectoration，dry mouth and sore throat caused by noninvasive ventilation ，and improveing of lung function． Results Lung function and blood gas analysis results were all improved in Two groups after treatment． In addition to 1 cases in observation group was send to ICU due to exacerbation，other cases were successfully weaned from non-invasive ventilator. The length of stay and ventilation time in experimental group were significantly lower than the control group． The ratio of sore throa， dry mouth and difficulty in expectoration in experimental group was statistically significante lower than the control group，P＜0. 05． 

Conclusion Oxygen-driven inhalation therapy can improve the therapeutic effect and quality of life in COPD patients with respiratory failure using non-invasive ventilation during hospitalization and worthy of clinical application．